HSP70 Polyclonal Antibody,Bioss,bs-0244R

Host

Rabbit

Reactivity

Human, Mouse, Rat, Pig, Chicken

Application

WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB725296042

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHSP70 Polyclonal Antibody
Cat. No.bs-0244R
Accession NumberP08107
Gene ID (Entrez)3303
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Pig, Chicken
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:ELISA1:500-1000 | IHC-F:FCM1:20-100 | IF:IHC-P1:200-400 | Flow-Cyt: | ICC/IF:
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

Synonyms

HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HSPA1A; HSX70

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