Heme Oxygenase 1 Antibody (YA6087),MedChemexpress,HY-P86395
Heme Oxygenase 1 Antibody (YA6087) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Heme Oxygenase 1.
Host
Rabbit
Reactivity
Human,Mouse,Rat
Application
WB,IHC-P,ICC/IF,IP,ELISA
Conjugate
Non-conjugated
Platform ID
BAB288000299

MedChemexpress
Master of Bioactive Molecules
Contact
Tel: 609-228-6898
Fax: 609-228-5909
Email:
Specifications
Scientific Background
HO-1 protein, through its catalytic activity, orchestrates the oxidative cleavage of heme at the alpha-methene bridge carbon, leading to the release of carbon monoxide (CO) and the generation of biliverdin IXalpha. Simultaneously, it liberates the central heme iron chelate as ferrous iron. This enzymatic process not only provides a mechanism for the breakdown of heme but also exerts a cytoprotective effect by preventing the sensitization of cells to programmed cell death or apoptosis. The ability of HO-1 to catabolize free heme underscores its crucial role in cellular defense mechanisms, contributing to cell survival and protection against various stressors.
Synonyms
Heme oxygenase 1 (HO-1) (EC 1.14.99.3)
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Primary Antibodies>IHC Antibodies
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