Hepatocyte Growth Factor Receptor / HGFR (MET) Antibody,Abbexa,abx025145

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Host

Mouse

Reactivity

Human, Mouse

Application

ELISA, WB, IHC, IF/ICC

Conjugate

Unconjugated

Platform ID

BAB619062462

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameHepatocyte Growth Factor Receptor / HGFR (MET) Antibody
Cat. No.abx025145
Accession NumberP08581
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsWB: 1/500 - 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
Molecular WeightCalculated MW: 156 kDa
ImmunogenPurified recombinant protein encoding the catalytic domain of human MET/HGFR.
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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