Hes1 Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-52568r-bf680-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, FCM, IF(IHC-P), IF(ICC)

Conjugate

AbBy Fluor-680

Platform ID

BAB841251621

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHes1 Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-52568r-bf680-100ul
Accession NumberQ14469
Gene ID (Entrez)3280
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationAbBy Fluor-680
ApplicationWB, FCM, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IF(IHC-P):IFIHC-P1:100-500 | IF(ICC):IFICC1:50-200
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

Synonyms

Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, bHLHb39, hHL, HES1

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