Histone Deacetylase 8 (HDAC8) Antibody,Abbexa,abx004469
HDAC8 Antibody is a Rabbit Polyclonal antibody against HDAC8. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, IF/ICC
Conjugate
Unconjugated
Platform ID
BAB495399320
Abbexa
Contact
Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951
Email:
Product Specifications
Specifications
NameHistone Deacetylase 8 (HDAC8) Antibody
Cat. No.abx004469
Accession NumberQ9BY41
Gene ID (Entrez)55869
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration> 0.2 mg/ml
Molecular WeightCalculated MW: 42 kDa Observed MW: 45 kDa
TargetHDAC8
ImmunogenSynthetic peptide corresponding to HDAC8. The exact sequence is proprietary.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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