Histone H2A Antibody (YA6211),MedChemexpress,HY-P86519

Histone H2A Antibody (YA6211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2A.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB413762433

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Product Specifications
Scientific Background
Synonyms

Specifications

NameHistone H2A Antibody (YA6211)
Cat. No.HY-P86519
Accession NumberP0C0S8/P04908/P20671/Q96KK5/Q6FI13/Q7L7L0
Gene ID (Entrez)8329/8332/8336/8969/3012/8335/3013/85235/723790/8337/92815
HostRabbit
RRIDAB_3719175
IsotypeIgG/Kappa
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:200-1:1000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6211
Molecular WeightPredicted band size: 14 kDa; Observed band size: 17 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Histone H2A is a crucial component of the nucleosome, a fundamental structural unit in chromatin organization. The nucleosome comprises a histone octamer composed of two copies each of H2A, H2B, H3, and H4, with one H3-H4 heterotetramer and two H2A-H2B heterodimers. This octameric assembly serves as a molecular spool around which approximately 147 base pairs of DNA are intricately wound, contributing to the compact and organized structure of chromatin. The intricate association of histones, including H2A, with DNA in the nucleosome is essential for the regulation of various cellular processes, including gene expression and DNA packaging.

Synonyms

HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p; HIST1H2AB; H2AFM; HIST1H2AE; H2AFA; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; HIS

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