Histone H2A.Z (Acetyl Lys7) antibody [RM222],Genetex,GTX33592
Host
Rabbit
Reactivity
Human
Application
WB ICC/IF ELISA
Conjugate
Unconjugated
Platform ID
BAB761381472
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]
Synonyms
H2A histone family member Z,H2A.Z1,H2A.z,H2A/z,H2AFZ,H2AZ,Histone H2A.Z,H2A.Z variant histone 1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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