Histone H2A.Z (Acetyl Lys7) antibody [RM222],Genetex,GTX33592

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB761381472

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameHistone H2A.Z (Acetyl Lys7) antibody [RM222]
Cat. No.GTX33592
Gene ID (Entrez)3015
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetH2AZ1
ImmunogenAn acetyl-peptide corresponding to Acetyl-Histone H2A.Z (Lys7).
PurityProtein A purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]

Synonyms

H2A histone family member Z,H2A.Z1,H2A.z,H2A/z,H2AFZ,H2AZ,Histone H2A.Z,H2A.Z variant histone 1

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