Human Microspherule protein 1 (MCRS1) ELISA Kit,Abbkine,KTE61688

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Platform ID

BAB273134333

Abbkine

Headquarters

3052 Stroop Hill Road, Apt 203, Atlanta 30303, Georgia, United States of America

Abbkine

Contact

Tel: +1-404-854-0155
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHuman Microspherule protein 1 (MCRS1) ELISA Kit
Cat. No.KTE61688
Accession NumberQ96EZ8
Gene ID (Entrez)10445
ShippingThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
StorageThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
Regulatory StatusResearch Use Only

Scientific Background

MCRS1 (Microspherule Protein 1) is a Protein Coding gene. Diseases associated with MCRS1 include Herpes Simplex and Pigmented Basal Cell Carcinoma. Among its related pathways are Chromatin organization and Transcription-Coupled Nucleotide Excision Repair (TC-NER). GO annotations related to this gene include histone acetyltransferase activity (H4-K5 specific) and histone acetyltransferase activity (H4-K16 specific). Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA Binds to RNA homopolymer poly(G) and poly(U).

Synonyms

MCRS1; ICP22BP; INO80Q; MCRS2; MSP58; P78; INO80 complex subunit Q; cell cycle-regulated factor (78 kDa)

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