Human Multidrug resistance-associated protein 6 (ABCC6) ELISA Kit,Abbkine,KTE60862

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Platform ID

BAB824870752

Abbkine

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Abbkine

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Tel: +1-404-854-0155
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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameHuman Multidrug resistance-associated protein 6 (ABCC6) ELISA Kit
Cat. No.KTE60862
Accession NumberO95255
Gene ID (Entrez)368
ShippingThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
StorageThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
Regulatory StatusResearch Use Only

Scientific Background

Multidrug resistance-associated protein 6 is member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multidrug resistance.Defects in ABCC6 are the cause of pseudoxanthoma elasticum (PXE). PXE is a disorder characterized by calcification of elastic fibers in skin, arteries and retina that results in dermal lesions with associated laxity and loss of elasticity, arterial insufficiency and retinal hemorrhages leading to macular degeneration.

Synonyms

ABCC6; ABC34; ARA; EST349056; MLP1; MOATE; MRP6; PXE; PXE1; URG7; ATP-binding cassette; sub-family C; member 6; anthracycline resistance-associated protein

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