Human Neuronal-specific septin-3 (SEPT3) ELISA Kit,Abbkine,KTE60824
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Platform ID
BAB259840717
Abbkine
Contact
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Specifications
Scientific Background
Neuronal-specific septin-3 belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in multiple transcript variants. SEP3 shares almost 100% sequence identity with mouse neuronal-specific septin-3 and rat brain-specific G-septin. Alternative splicing leads to 3 SEP3 isoforms, SEP3A, SEP3B, and SEP3C, which encode proteins of 345, 337, and 71 amino acids, respectively. SEP3A and SEP3B contain a set of consensus sequence motifs for GTP binding, 2 predicted phosphorylation sites for PKG, and a conserved binding motif for SH3 domain-containing proteins.
Synonyms
SEPT3; CTA-250D10.3; MGC133218; SEP3; bK250D10.3; neuronal-specific septin 3
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