Human Prostaglandin reductase 2 (PTGR2) ELISA Kit,Abbkine,KTE61067
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Platform ID
BAB398296755
Abbkine
Contact
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Specifications
Scientific Background
PTGR2 is an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. ZADH1 has a domain characteristic of the zinc-containing ADH family , a proline-rich motif, and a putative NADP(+)-binding domain. RT-PCR detected ubiquitous expression of the shorter ZADH1 transcript (ZADH1b), with highest expression in kidney, liver, pancreas, prostate, and heart, followed by lung, skeletal muscle, testis, small intestine, and brain. Expression was low in all other tissues examined.
Synonyms
PTGR2; DKFZp686P10120; FLJ39091; FLJ99229; PGR2; ZADH1; 15-oxoprostaglandin-delta13-reductase; zinc binding alcohol dehydrogenase; domain containing 1
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