Human Protein phosphatase Slingshot homolog 1 (SSH1) ELISA Kit,Abbkine,KTE60366

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Platform ID

BAB773084357

Abbkine

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Abbkine

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Tel: +1-404-854-0155
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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameHuman Protein phosphatase Slingshot homolog 1 (SSH1) ELISA Kit
Cat. No.KTE60366
Accession NumberQ8WYL5
Gene ID (Entrez)54434
ShippingThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
StorageThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
Regulatory StatusResearch Use Only

Scientific Background

The ADF (actin-depolymerizing factor)/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo. Transcript analysis suggested that at least 6 polypeptides would be produced from these genes. SSH1 encodes 3 isoforms, SSH1L (1,049 amino acids), SSH1S (692 amino acids), and SSH1B (148 amino acids), and SSH2 encodes 2 isoforms, SSH2 (449 amino acids) and SSH2B (195 amino acids). The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs and are unique to the SSH family.

Synonyms

SSH1; FLJ21928; FLJ38102; KIAA1298; SSH1L; slingshot 1

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