Human Protein phosphatase Slingshot homolog 2 (SSH2) ELISA Kit,Abbkine,KTE60367

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Platform ID

BAB197259506

Abbkine

Headquarters

3052 Stroop Hill Road, Apt 203, Atlanta 30303, Georgia, United States of America

Contact

Tel: +1-404-854-0155
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Product Specifications
Scientific Background
Synonyms

Specifications

NameHuman Protein phosphatase Slingshot homolog 2 (SSH2) ELISA Kit
Cat. No.KTE60367
Accession NumberQ76I76
Gene ID (Entrez)85464
ShippingThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
StorageThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
Regulatory StatusResearch Use Only

Scientific Background

Two of the human proteins, SSH1L and SSH2, were enzymatically active when reacted with an artificial substrate, p-nitrophenyl phosphate. SSH3 did not exhibit activity toward p-nitrophenyl phosphate, and its expression did not reduce the level of P-cofilin in COS-7 cells. In mammalian cells, SSH1L and SSH2 suppressed LIMK1-induced actin reorganization. Furthermore, ssh, SSH1L, and SSH2 dephosphorylated P-cofilin in cultured cells and in cell-free assays. SSH1 encodes 3 isoforms, SSH1L, SSH1S, and SSH1B, and SSH2 encodes 2 isoforms, SSH2 and SSH2B. The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs (domains A and B) and are unique to the SSH family.

Synonyms

SSH2; KIAA1725; MGC78588; SSH-2; slingshot 2

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