Human Transportin-2 (TNPO2) ELISA Kit,Abbkine,KTE60182

• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.

Platform ID

BAB075795308

Abbkine

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Abbkine

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Tel: +1-404-854-0155
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHuman Transportin-2 (TNPO2) ELISA Kit
Cat. No.KTE60182
Accession NumberO14787
Gene ID (Entrez)30000
ShippingThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
StorageThe unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.
Regulatory StatusResearch Use Only

Scientific Background

Transportin-2 (KPNB2) interacts directly and specifically with M9, the bidirectional transport signal of the nuclear shuttling protein hnRNPA1 and mediates hnRNPA1 nuclear import. In the course of isolating additional transportin-1 cDNAs, Siomi et al. (1997) isolated cDNAs encoding a related protein that they designated 'transportin-2.' The sequence of the predicted 894-amino acid protein shares 84% identity with that of transportin-1. One notable difference is that transportin-2 contains a short extra sequence within the region corresponding to the M9-interacting domain of transportin-1. Far Western blotting showed that transportin-2 and transportin-1 have different substrate specificities. Siomi et al. (1997) suggested that the insert in transportin-2 modifies its interaction with import substrates.

Synonyms

TNPO2; FLJ12155; IPO3; KPNB2B; TRN2; importin 3; karyopherin beta 2b; transportin; transportin 2 (importin 3; karyopherin beta 2b)

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