Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) ELISA Kit,Abbkine,KTE60222
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Platform ID
BAB709903434
Abbkine
Contact
Tel: +1-404-854-0155
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Specifications
Scientific Background
Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system.TACI is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It was orignially discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases.
Synonyms
TNFRSF13B; CD267; CVID; FLJ39942; MGC133214; MGC39952; TACI; TNFRSF14B; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B
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