IDS antibody,Genetex,GTX12202

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB960131084

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameIDS antibody
Cat. No.GTX12202
Gene ID (Entrez)3423
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetIDS
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase(430-448aa ELCREGKNLLKHFRFRDLE).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA,0.025% Thimerosal, 0.025% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

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