IGF1R alpha antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free),Genetex,GTX42246

Host

Mouse

Reactivity

Human

Application

WB IHC-P FCM Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB715892053

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIGF1R alpha antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free)
Cat. No.GTX42246
Gene ID (Entrez)3480
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P FCM Neutralizing /Inhibition
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIGF1R
ImmunogenPurified human placental IGF-I receptor.
PurityProtein G purifiedFrom tissue culture supernatant
Endotoxin LevelLow Endotoxin
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Synonyms

insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13

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