IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody,Genetex,GTX55013

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB569928356

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody
Cat. No.GTX55013
Gene ID (Entrez)3480
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetIGF1R
ImmunogenKLH-conjugated synthetic peptide encompassing a sequence within the C-term region of IGF1R. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Synonyms

insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13

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