IL-6 Rabbit mAb,ABclonal,A27935

Reactivity

Mouse, Rat

Application

WB, IP, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB660850899

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameIL-6 Rabbit mAb
Cat. No.A27935
Accession NumberP20607
Gene ID (Entrez)24498
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IP:0.5 μg-4 μg antibody for 900 μg-1100 μg extracts of whole cells | IF/ICC:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC73456
Molecular Weight24 kDa
ImmunogenRecombinant protein (or fragment). This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of cell communication; and positive regulation of metabolic process. Located in extracellular space. Used to study several diseases, including acute necrotizing pancreatitis; disseminated intravascular coagulation; hypertension (multiple); impotence; and steatotic liver disease. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); auditory system disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6).

Synonyms

ILg6; Ifnb2

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