IL-6R Antibody,MedChemexpress,HY-P81629

IL-6R Antibody is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-6R.

Host

Mouse

Reactivity

Human,Mouse

Application

WB,IHC-P,ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB696183128

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameIL-6R Antibody
Cat. No.HY-P81629
Accession NumberP08887
Gene ID (Entrez)3570
HostMouse
RRIDAB_3103739
IsotypeIgG1
SensitivityEndogenous
ReactivityHuman,Mouse
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC,ELISA
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:100-1:200; ICC/IF: 1:50-1:200; FC: 1:50-1:100; ELISA: 1:10000
ClonalityMonoclonal
Clone NumberYA3522
Molecular WeightPredicted band size: 52 kDa;Observed band size: 52 kDa
ImmunogenPurified recombinant fragment of human CD126 expressed in E. Coli.
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS with 0.05% sodium azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

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Scientific Background

The related gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of The protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and The receptor are implicated in the pathorelated genesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in The related gene. A pseudorelated gene of The related gene is found on chromosome 9.

Synonyms

CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ

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