IL1 Receptor antagonist antibody [2V23],Genetex,GTX52843

Host

Rat

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB935620326

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL1 Receptor antagonist antibody [2V23]
Cat. No.GTX52843
Gene ID (Entrez)3557
HostRat
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetIL1RN
ImmunogenHuman recombinant IL-1ra
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]

Synonyms

DIRA , ICIL1RA , IL1F3 , IL1RA , IL1RN , IL1ra , IL1ra3 , IRAP , MVCD4 , interleukin 1 receptor antagonist , IL1 Receptor antagonist

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