IL1 beta antibody [6E10],Genetex,GTX28319

Host

Mouse

Reactivity

Human

Application

ELISA IHC

Conjugate

Unconjugated

Platform ID

BAB308919907

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL1 beta antibody [6E10]
Cat. No.GTX28319
Gene ID (Entrez)3553
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA IHC
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetIL1B
ImmunogenRecombinant human IL-1, beta.
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Synonyms

interleukin 1 beta , IL-1 , IL1-BETA , IL1F2

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