IL10 antibody [GT5111],Genetex,GTX632359

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB832747200

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL10 antibody [GT5111]
Cat. No.GTX632359
Gene ID (Entrez)3586
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr
ClonalityMonoclonal
Concentration1.19 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIL10
ImmunogenRecombinant protein encompassing a sequence within the center region of human IL10. The exact sequence is proprietary.
PurityAffinity purified by Protein G.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

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