IL10 antibody [JES5-2A5],Genetex,GTX27379

Host

Rat

Reactivity

Mouse

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB057495591

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL10 antibody [JES5-2A5]
Cat. No.GTX27379
Gene ID (Entrez)16153
HostRat
IsotypeIgG2
ReactivityMouse
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIl10
ImmunogenThis antibody was generated against the recombinant mouse IL-10 expressed in E. coli. It has not been reported to cross-react with rat IL-10.
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
Formulation10mM NaH₂PO₄, 150mM NaCl,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]

Synonyms

interleukin 10 , CSIF , Il-10

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