IL12 antibody,Genetex,GTX20050

Host

Mouse

Reactivity

Human

Application

IHC-Fr ELISA RIA

Conjugate

Unconjugated

Platform ID

BAB110281506

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL12 antibody
Cat. No.GTX20050
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-Fr ELISA RIA
ClonalityMonoclonal
Concentration0.7 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant human interleukin-12 produced in Baculovirus.
PurityProtein A affinity purified
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.

Synonyms

Subunit P40 , Natural Killer Cell Stimulatory Factor2 , Natural Killer Cell Stimulatory Factor 2 , Interleukin 12B , 40 kD Subunit , Cytotoxic lymphocyte maturation factor 40 kDa subunit , T cell stimulating factor , Cytotoxic lymphocyte maturation factor40 kDa subunit , CLMF2 , Interleukin12B , TSF , Cytotoxic Lymphocyte Maturation Factor 2 , IL12 , Cytotoxic Lymphocyte Maturation Factor2 , HGNC:5970 , IL1 , NKSF2 , CLMF , IL-12B , NKSF , IL 12B , IL12B

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