IL17A antibody [MT504] (Biotin),Genetex,GTX02966-02

Host

Mouse

Reactivity

Human, Sheep, Bovine, Dog, Pig, Monkey, Horse

Application

FCM ELISA Sandwich ELISA

Conjugate

Biotin Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Platform ID

BAB721311979

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL17A antibody [MT504] (Biotin)
Cat. No.GTX02966-02
Gene ID (Entrez)3605
HostMouse
IsotypeIgG1
ReactivityHuman, Sheep, Bovine, Dog, Pig, Monkey, Horse
ConjugationBiotin Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
ApplicationFCM ELISA Sandwich ELISA
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIL17A
ImmunogenRecombinant human IL-17A
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

Synonyms

CTLA8,IL17,IL17A,interleukin 17A

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