IL17A antibody [TC11-18H10],Genetex,GTX16323

Host

Rat

Reactivity

Mouse

Application

WB FCM Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB229246904

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL17A antibody [TC11-18H10]
Cat. No.GTX16323
Gene ID (Entrez)16171
HostRat
IsotypeIgG1
ReactivityMouse
ConjugationUnconjugated
ApplicationWB FCM Neutralizing /Inhibition
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIl17a
ImmunogenE. coli expressed recombinant mouse IL-17
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]

Synonyms

interleukin 17A , Ctla-8 , Ctla8 , IL-17 , IL-17A , Il17

Category Paths

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