IL1F5 antibody,Genetex,GTX48763

Host

Rabbit

Reactivity

Bovine

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB050987452

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL1F5 antibody
Cat. No.GTX48763
Gene ID (Entrez)518514
HostRabbit
IsotypeIgG
ReactivityBovine
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIL36RN
ImmunogenRecombinant protein raised in yeast, corresponding to the 155 amino acids of the mature bovine IL-1F5 protein.
PurityProtein A purifiedFrom serum
Appearance/FormLiquid
Formulation20mM Potassium Phosphate, 150mM NaCl,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Interleukin-1F5 is a recently discovered cytokine which was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6) in humans. There is very little published regarding the bovine IL1F5 protein. In the human, this gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Expression of the gene appears to be restricted to various epithelial cell populations. Costelloe et al (2008) have identified SIGIRR [single immunoglobulin domain-containing IL1R-related protein] as a receptor for human IL1F5.

Synonyms

interleukin 36 receptor antagonist , IL1F5

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