IL2 Receptor alpha antibody [MEM-140] (Biotin),Genetex,GTX78341

Host

Mouse

Reactivity

Human

Application

FCM IP

Conjugate

Biotin The reagent is free of unconjugated biotin.

Platform ID

BAB368080232

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL2 Receptor alpha antibody [MEM-140] (Biotin)
Cat. No.GTX78341
Gene ID (Entrez)3559
HostMouse
IsotypeIgM
ReactivityHuman
ConjugationBiotin The reagent is free of unconjugated biotin.
ApplicationFCM IP
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIL2RA
ImmunogenPHA-activated peripheral blood leucocytes
PurityPurified IgM
Appearance/FormLiquid
FormulationTBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Synonyms

CD25 , IDDM10 , IL2R , IL2RA , IMD41 , TCGFR , interleukin 2 receptor subunit alpha , p55 , IL2-R alpha

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