IL2 Receptor alpha antibody [MEM-181],Genetex,GTX75869

Host

Mouse

Reactivity

Human

Application

FCM

Conjugate

Unconjugated

Platform ID

BAB051775809

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIL2 Receptor alpha antibody [MEM-181]
Cat. No.GTX75869
Gene ID (Entrez)3559
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationFCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIL2RA
ImmunogenPHA-activated peripheral blood leucocytes
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Synonyms

CD25 , IDDM10 , IL2R , IL2RA , IMD41 , TCGFR , interleukin 2 receptor subunit alpha , p55 , IL2-R alpha

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