IP3 Receptor Polyclonal Antibody,Bioss,bs-8869R

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB064389521

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIP3 Receptor Polyclonal Antibody
Cat. No.bs-8869R
Accession NumberQ14643
Gene ID (Entrez)3708
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationFlow-Cyt, ICC/IF
Working DilutionsFlow-Cyt:FCM1:200 | ICC/IF:
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Synonyms

ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1

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