IRF1 Antibody (YA3118),MedChemexpress,HY-P83373

IRF1 Antibody (YA3118) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IRF1.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-F,IHC-P,ICC/IF,IP

Conjugate

Non-conjugated

Platform ID

BAB832040414

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameIRF1 Antibody (YA3118)
Cat. No.HY-P83373
Accession NumberP10914
Gene ID (Entrez)3659
HostRabbit
RRIDAB_3105486
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-F,IHC-P,ICC/IF,IP
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; IHC-F: 1:50-1:100; ICC/IF: 1:50-1:200; IP: 1:20
ClonalityRecombinant,Monoclonal
Clone NumberYA3118
Molecular WeightPredicted band size: 37 kDa; Observed band size: 48 kDa
ImmunogenRecombinant protein of human IRF1 aa126-325 aa126-325.
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

The protein encoded by The related gene is a transcriptional regulator and tumor suppressor, serving as an activator of related genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of related genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. The protein represses the transcription of several other related genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in The related gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer.

Synonyms

IRF1; Interferon regulatory factor 1; IRF-1

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