IRF4 / MUM1 antibody,Genetex,GTX129135

Host

Rabbit

Reactivity

Human

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB339916286

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIRF4 / MUM1 antibody
Cat. No.GTX129135
Gene ID (Entrez)3662
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetIRF4
ImmunogenRecombinant protein encompassing a sequence within the center region of human IRF4 / MUM1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Synonyms

interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8

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