IRS2 (pY978) Antibody,Abbexa,abx032045

Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Host

Rabbit

Reactivity

Human

Application

ELISA, DB

Conjugate

Unconjugated

Platform ID

BAB438916560

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameIRS2 (pY978) Antibody
Cat. No.abx032045
Accession NumberQ9Y4H2
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, DB
Working DilutionsDB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 137 kDa
ImmunogenKLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.
PurityPurified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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