ISCU antibody [N1C3],Genetex,GTX115709

Host

Rabbit

Reactivity

Human, Mouse

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB074098882

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameISCU antibody [N1C3]
Cat. No.GTX115709
Gene ID (Entrez)23479
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration0.66 mg/ml (Please refer to the vial label for the specific concentration.)
TargetISC
ImmunogenRecombinant protein encompassing a sequence within the center region of human ISCU. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq]

Synonyms

iron-sulfur cluster assembly enzyme , 2310020H20Rik , HML , ISU2 , NIFU , NIFUN , hnifU

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