IVNS1ABP antibody,Genetex,GTX118817
Host
Rabbit
Reactivity
Human, Mouse
Application
WB IHC-P
Conjugate
Unconjugated
Platform ID
BAB829871110

Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Synonyms
influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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