Importin Alpha 5/KPNA1 Rabbit mAb,ABclonal,A24117

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB782515001

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameImportin Alpha 5/KPNA1 Rabbit mAb
Cat. No.A24117
Accession NumberP52294
Gene ID (Entrez)3836
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, IHC-P, ELISA
Working DilutionsWB:1:30000 - 1:120000 | IF/ICC:1:200 - 1:800 | IF-P:1:200 - 1:800 | IHC-P:1:200 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC65389
Molecular Weight62kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Synonyms

RCH2; SRP1; IPOA5; NPI-1; Importin Alpha 5/KPNA1

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