Insulin Receptor R (8A1) Monoclonal Antibody,Bioss,bsm-54080R

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P

Conjugate

Unconjugated

Platform ID

BAB344400109

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameInsulin Receptor R (8A1) Monoclonal Antibody
Cat. No.bsm-54080R
Accession NumberP14616
Gene ID (Entrez)3645
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400
ClonalityMonoclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Scientific Background

The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Synonyms

Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IRR, INSRR

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.