Integrin Alpha 8 (ITGA8) Antibody,Abbexa,abx026339
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Host
Rabbit
Reactivity
Human
Application
ELISA, WB, IHC
Conjugate
Unconjugated
Platform ID
BAB243742702
Abbexa
Contact
Tel: +44 (0) 1223 755950
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Product Specifications
Specifications
NameIntegrin Alpha 8 (ITGA8) Antibody
Cat. No.abx026339
Accession NumberP53708
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsWB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 117 kDa
ImmunogenKLH-conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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