Integrin alpha 3 antibody,Genetex,GTX11993

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB081995090

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameIntegrin alpha 3 antibody
Cat. No.GTX11993
Gene ID (Entrez)3675
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetITGA3
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3(51-67aa LFGYSVALHRQTERQQR), identical to the related rat and mouse sequences.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA,0.025% Thimerosal, 0.025% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]

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