Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free),Genetex,GTX41962

Host

Mouse

Reactivity

Human

Application

IHC-Fr FCM Functional Assay

Conjugate

Unconjugated

Platform ID

BAB590329823

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIntegrin alpha 4 antibody [44H6] (Low endotoxin, azide free)
Cat. No.GTX41962
Gene ID (Entrez)3676
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-Fr FCM Functional Assay
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetITGA4
ImmunogenHOON pre-B leukaemia cell line.
PurityPurified by ion exchange chromatographyFrom tissue culture supernatant
Endotoxin LevelLow Endotoxin
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Synonyms

integrin subunit alpha 4 , CD49D , IA4

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