Integrin alpha 5 Recombinant Antibody,Bioss,bsm-61357r-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IF(IHC-P), IP

Conjugate

Unconjugated

Platform ID

BAB991102187

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameIntegrin alpha 5 Recombinant Antibody
Cat. No.bsm-61357r-100ul
Accession NumberP08648
Gene ID (Entrez)3678
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF(IHC-P), IP
Working DilutionsWB:1:500-2000 | IHC-P:IHC-P1:50-200 | IHC-F:IHC-F1:50-200 | IF(IHC-P):IFIHC-P1:50-200 | IP:IP1:20-50
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.

Synonyms

Integrin alpha-5; VLA-5; CD49e; ITGA5; FNRA.

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