Integrin alpha 6 antibody [MP 4F10],Genetex,GTX40142

Host

Mouse

Reactivity

Human

Application

IHC-Fr FCM IP

Conjugate

Unconjugated

Platform ID

BAB024600124

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameIntegrin alpha 6 antibody [MP 4F10]
Cat. No.GTX40142
Gene ID (Entrez)3655
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-Fr FCM IP
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetITGA6
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Synonyms

CD49f , ITGA6 , ITGA6B , VLA6 , integrin subunit alpha 6 , Integrin alpha 6 , Integrin α6

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