JNK (phospho Thr183/Tyr185) antibody,Genetex,GTX24821

Host

Rabbit

Reactivity

Human, Mouse, Rat, Pig, Primate

Application

WB ICC/IF IHC-P IP IHC

Conjugate

Unconjugated

Platform ID

BAB678210149

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background

Specifications

NameJNK (phospho Thr183/Tyr185) antibody
Cat. No.GTX24821
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Pig, Primate
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP IHC
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
ImmunogenThe antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human JNK1 and 2 that contains threonine 183 and tyrosine 185. This region is conserved among many species including mouse, rat, chicken, nematode, fruit fly, and in JNK3.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 0.1% BSA, 50% Glycerol,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Cellular oncogenes, or proto-oncogenes, play pivotal roles in cellular communication pathways that regulate normal growth, development and differentiation. The cellular oncogene families fos and jun encode nuclear proteins that can function as transcription factors. The fos family of nuclear oncogenes encode cFos, FosB, (fos-related antigen) Fra1, and Fra2. The jun family member, cJun, is phosphorylated by another kinase termed cJun N-terminal kinase (JNK).

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