Jumonji Domain-Containing Protein 2B (JMJD2B) Antibody,Abbexa,abx026520

KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20' and only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB195998044

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Abbexa

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Email:

[email protected]

Product Specifications

Specifications

NameJumonji Domain-Containing Protein 2B (JMJD2B) Antibody
Cat. No.abx026520
Accession NumberO94953
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 122 kDa
TargetKDM4B
ImmunogenKLH-conjugated synthetic peptide between 428-459 amino acids from the N-terminal region of human JMJD2B.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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