K63-linkage Specific Polyubiquitin Rabbit pAb- ABclonal,ABclonal,A18164
Reactivity
Human, Mouse, Rat, Other (Wide Range Predicted)
Application
DB, ELISA
Platform ID
BAB958652943
ABclonal
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Product Specifications
Scientific Background
Specifications
NameK63-linkage Specific Polyubiquitin Rabbit pAb- ABclonal
Cat. No.A18164
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range Predicted)
ApplicationDB, ELISA
Working DilutionsDB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight15-200kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
Ubiquitination,onetypeofthemostcommonpost-translationalmodification,mediatestheregulationofproteinhomeostasisinvivo.SinceubiquitinitselfcontainsmultiplelysineresiduesandoneN-terminalfreeaminogroup,eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development （PMID: 19217402，PMCID: PMC3008764）.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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