[KD Validated] Bcl-2 Rabbit PolymAb®,ABclonal,A27315PM

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB457603447

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

Name[KD Validated] Bcl-2 Rabbit PolymAb®
Cat. No.A27315PM
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:3000 - 1:18000 | IHC-P:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight26kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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