[KD Validated] Bcl-2 Rabbit mAb,ABclonal,A19693

Reactivity

Human, Mouse

Application

WB, IHC-P, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB845895828

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] Bcl-2 Rabbit mAb
Cat. No.A19693
Accession NumberP10415
Gene ID (Entrez)596
RRIDAB_2862738
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, IHC-P, IP, ELISA
Working DilutionsWB:1:3000 - 1:15000 | IHC-P:1:1000 - 1:4000 | IP:0.5μg-4μg antibody for 100μg-300μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0173
Molecular Weight26 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Synonyms

Bcl-2; PPP1R50

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