[KD Validated] ECH1 Rabbit mAb,ABclonal,A27290

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB037037829

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] ECH1 Rabbit mAb
Cat. No.A27290
Accession NumberQ13011
Gene ID (Entrez)1891
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, ELISA
Working DilutionsWB:1:12000 - 1:72000 | IHC-P:1:1000 - 1:10000 | IF/ICC:1:100 - 1:400 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC71050
Molecular Weight35kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Synonyms

HPXEL

Category Paths

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