[KD Validated] ERK1 Rabbit mAb,ABclonal,A19561

Reactivity

Human, Mouse

Application

WB, IP, IF/ICC, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB906777855

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] ERK1 Rabbit mAb
Cat. No.A19561
Accession NumberP27361
Gene ID (Entrez)5595
RRIDAB_2862668
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IF-P, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:6000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IF/ICC:1:100 - 1:800 | IF-P:1:100 - 1:800 | IHC-P:1:200 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC2591
Molecular Weight44kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Synonyms

ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; K1

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